Mayo Clinic's approach

Mayo Clinic doctors have extensive experience using bone marrow transplants to treat a variety of conditions, including cancers. Mayo Clinic offers bone marrow transplants for adults and children using the patient's own cells (autologous transplant), cells from a donor (allogeneic transplant) or using cells from an umbilical cord (cord blood transplant).

People who choose Mayo Clinic for their care receive comprehensive, compassionate and personalized attention from doctors and staff who are committed to providing exactly the care they need.

Teamwork

At Mayo Clinic, doctors who specialize in blood diseases (hematologists) form a multidisciplinary team with other experts to provide personalized, whole-person care to adults and children undergoing bone marrow transplants.

Image for Bone Marrow transplant

Your transplant team may include hematologists, cancer specialists (oncologists), mental health specialists (psychologists and psychiatrists), a bone marrow transplant scheduling coordinator, transfusion medicine nurses, trained and specialized nurses, physician assistants, social workers, a nurse coordinator, a clinical nurse specialist, a dietitian, pharmacists, a chaplain and a child life specialist for children undergoing bone marrow transplant.

Children and adolescents undergoing bone marrow transplants receive care at the Children's Center at Mayo Clinic's campus in Minnesota. At Mayo Clinic's campus in Arizona, pediatric experts collaborate with the Phoenix Children's Hospital to provide care to young patients. Together the two oversee a single bone marrow transplant program for children. Pediatric patients receive care from Mayo Clinic specialists in Florida through a partnership with Nemours Children's Specialty Care and Wolfson Children's Hospital.

Image of Mayo Clinic doctors and staff working together Working together

Mayo Clinic doctors and staff collaborate to provide you with exactly the care you need.

Experience

Mayo Clinic doctors have extensive experience performing bone marrow transplants for adults and children with a variety of cancerous and noncancerous diseases. Each year, more than 700 people undergo bone marrow transplants at Mayo Clinic.

The first bone marrow transplant at Mayo Clinic occurred in 1963. Bone marrow transplant procedures are performed by Mayo Clinic doctors in Arizona, Florida and Minnesota.

The long history of bone marrow transplants performed at Mayo Clinic means that doctors are prepared with the knowledge and resources to provide you with expert, personalized care.

Image of staff providing compassionate care Providing compassionate care

Mayo Clinic experts draw on their extensive experience to provide personalized care to people considering bone marrow transplant

Bringing research advances to patient care

Mayo Clinic doctors and scientists are involved in cutting-edge research that allows them to apply the latest advances to patient care.

Innovations include:

  • Haploidentical transplant to use stem cells from donors who aren't perfect matches. Research is helping doctors understand how to reduce the risk of complications and improve recovery for people whose stem cell donors aren't perfect matches.
  • Reduced-intensity conditioning to use lower doses of chemotherapy and radiation before a transplant. Researchers are studying new conditioning regimens that will allow older people and those who aren't healthy enough for conditioning to undergo bone marrow transplants.
  • Cord blood transplant using stored and frozen umbilical cord blood. There are fewer stem cells in cord blood, but those stem cells can grow more blood cells than can those collected from bone marrow. Using cells from cord blood reduces the risk of graft-versus-host disease. Researchers are identifying the best ways to use cord blood for bone marrow transplants.
  • Expanding indications for bone marrow transplant to use this treatment for a wider variety of conditions, including complicated and rare diseases.

At Mayo Clinic, some bone marrow transplants are performed as hospital-based outpatient procedures, which reduces the amount of time you'll need to spend in the hospital.

Nationally recognized expertise

Mayo Clinic bone marrow transplant specialists are respected for their knowledge, experience and expertise.

Mayo Clinic in Rochester, Minn., Mayo Clinic in Jacksonville, Fla., and Mayo Clinic in Scottsdale, Ariz., are ranked among the Best Hospitals for cancer by U.S. News & World Report.

Oct. 13, 2016
References
  1. AskMayoExpert. Hematopoietic stem cell transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2015.
  2. Hoffman R, et al. Overview of hematopoietic stem cell transplantation. In: Hematology: Basic Principles and Practice. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2013. http://www.clinicalkey.com. Accessed July 8, 2016.
  3. Blood-forming stem cell transplants. National Cancer Institute. http://www.cancer.gov/about-cancer/treatment/types/stem-cell-transplant/stem-cell-fact-sheet. Accessed July 8, 2016.
  4. Majhail NS, et al. Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation. Biology of Blood and Marrow Transplantation. 2012;18:348.
  5. Diseases treatable by transplants. National Marrow Donor Program. https://bethematch.org/transplant-basics/how-transplants-work/diseases-treatable-by-transplants/. Accessed July 8, 2016.
  6. AskMayoExpert. Graft-versus-host disease. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
  7. Blood and marrow stem cell transplantation. Leukemia & Lymphoma Society. http://www.lls.org/resource-center/download-or-order-free-publications. Accessed July 8, 2016.
  8. Barbara Woodward Lips Patient Education Center. Autologous stem cell transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
  9. Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. July 20, 2016.